Transport is your number one priority if you are visitor in Rome expecting to see the word you so ardently admired on the television. You will need to have an escort take you around the city at all times or even better hire a car so that you can drive yourself around. On the other hand, the hotels in Rome give taxis to their clients at a small fee and a guide at the same time so in this case you are able to kill tree birds with one stone; the transport issue will be solved , the driving issue will be solved as even the guide will be at you call.
Depending on where you come from, driving in Rome can be quite a tricky aspect of your travel. Some countries drive on the left side of the road and some drive on the right side of the road. Therefore, before you decide to hire a car to drive yourself around you should be very sure which side of the lane you will be driving on as well as all the Roman traffic rules; if in doubt, hire a taxi.
Transport can be walking on a footpath if need be. One should note at some time in your trip you will be needed to walk so as to better understand the city and really enjoy yourself. A bicycle can also be a good mode of transport as you are able to see city well. It is also a cheaper way of handling your business in the city compared to the use of a taxi, which might cost you at least five times the bicycle ride. Another form of transport in Rome is the use of a horse cart, which is a bit more expensive than the use of a taxi but at the end of the day you enjoy the ride and you get to see the whole city and even get to interact very closely with the community. This is what a holiday or a visit in the Roman Capital would and should mean.
If you do not take the right transport, you are sure to miss a lot e.g. if you decide to take a train you should note that you will not be able to see everything that you were to see in the city as it will take you outside the city. You should note that depending on what you want you could also hitchhike around the city and save a lot of money and at the same time get a free tour guide every time you get into the new car. You would also make good friends all along the way. Therefore, depending on your need and your expectations of the trip, you should choose the best mode of transport appropriately. To some extent, you might not need any transport at all if you are in a very tall hotel and you might just have to go to the tallest point of the building and just look round.